Plant Transcription Factor Database
Previous version: v3.0
Solanum tuberosum
HSF Family
Species TF ID Description
PGSC0003DMP400000756HSF family protein
PGSC0003DMP400004801HSF family protein
PGSC0003DMP400004805HSF family protein
PGSC0003DMP400004806HSF family protein
PGSC0003DMP400004807HSF family protein
PGSC0003DMP400005485HSF family protein
PGSC0003DMP400005713HSF family protein
PGSC0003DMP400007176HSF family protein
PGSC0003DMP400008251HSF family protein
PGSC0003DMP400011443HSF family protein
PGSC0003DMP400014004HSF family protein
PGSC0003DMP400014364HSF family protein
PGSC0003DMP400014459HSF family protein
PGSC0003DMP400014460HSF family protein
PGSC0003DMP400025228HSF family protein
PGSC0003DMP400026069HSF family protein
PGSC0003DMP400026070HSF family protein
PGSC0003DMP400028423HSF family protein
PGSC0003DMP400028424HSF family protein
PGSC0003DMP400030290HSF family protein
PGSC0003DMP400030540HSF family protein
PGSC0003DMP400033605HSF family protein
PGSC0003DMP400033606HSF family protein
PGSC0003DMP400033608HSF family protein
PGSC0003DMP400033610HSF family protein
PGSC0003DMP400033615HSF family protein
PGSC0003DMP400033616HSF family protein
PGSC0003DMP400046950HSF family protein
PGSC0003DMP400046951HSF family protein
PGSC0003DMP400047457HSF family protein
PGSC0003DMP400048367HSF family protein
PGSC0003DMP400048368HSF family protein
PGSC0003DMP400048369HSF family protein
PGSC0003DMP400049433HSF family protein
PGSC0003DMP400049435HSF family protein
PGSC0003DMP400049438HSF family protein
PGSC0003DMP400051767HSF family protein
PGSC0003DMP400055694HSF family protein
PGSC0003DMP400056532HSF family protein
PGSC0003DMP400063465HSF family protein
PGSC0003DMP400065338HSF family protein
HSF Family Introduction

Heat stress transcription factors (Hsfs) are the major regulators of the plant heat stress (hs) response. Sequencing of the Arabidopsis genome revealed the existence of 21 open-reading frames (ORFs) encoding putative Hsfs assigned to classes A-C. Here we present results of a functional genomics approach to the Arabidopsis Hsf family focused on the analysis of their C-terminal domains (CTDs) harboring conserved modules for their function as transcription factors and their intracellular localization. Using reporter assays in tobacco protoplasts and yeast as well as glutathione-S-transferase (GST) pull-down assays, we demonstrate that short peptide motifs enriched with aromatic and large hydrophobic amino acid (aa) residues embedded in an acidic surrounding (AHA motifs) are essential for transcriptional activity of class A Hsfs. In contrast to this, class B and C Hsfs lack AHA motifs and have no activator function on their own. We also provide evidence for the function of a leucine (Leu)-rich region centered around a conserved QMGΦL motif at the very C-terminus as a nuclear export signal (NES) of class A Hsfs. Sequence comparison indicates that the combination of a C-terminal AHA motif with the consensus sequence FWxxF/L,F/I/L as well as the adjacent NES represents a signature domain for plant class A Hsfs, which allowed to identify more than 60 new Hsfs from the expressed sequence tag (EST) database.

Kotak S, Port M, Ganguli A, Bicker F, von Koskull-Doring P.
Characterization of C-terminal domains of Arabidopsis heat stress transcription factors (Hsfs) and identification of a new signature combination of plant class A Hsfs with AHA and NES motifs essential for activator function and intracellular localization.
Plant J, 2004. 39(1): p. 98-112.
PMID: 15200645